I use Seaguar fluorocarbon for just about everything. I used to only use it for my spinning rods and jig and worm rods, but over the last few years, I have seen the benefits for other uses. I just read an article on Wired2Fish about using fluorocarbon for spinnerbaits. It's a great piece on why you should expand your use of fluorocarbon. One of the things I really agree with is "We believe it's actually better for a number of reasons. One reason is abrasion resistance and toughness, but another is feel." Those are just two of the reasons I like using fluoro on spinnerbaits and all reaction baits in general. I also like to use it on my cranking as I feel it sinks better and lets the bait dive deeper than it would on mono.
As always, it's important to have the right setup, and like they said in the article "the key to using Seaguar InvizX fluorocarbon for spinnerbaits is the right rod and reel." You can have the best line ever made, but without the whole package it's hard to get the full effect.
If you aren't using fluorocarbon on reaction baits you are really missing out.